Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971323 | 0.95 | MAPT (0.39) | MAPTF2RL3MEN1KMT2ALMNA | |
| SCHEMBL8559970 | 0.80 | MAPT (0.37) | MAPTF2RL3MEN1KMT2ALMNA | |
| SCHEMBL7985009 | 0.71 | MAPT (0.56) | MAPTF2RL3MEN1KMT2ALMNA | |
| SCHEMBL8156893 | 0.69 | KDM4E (0.41) | MAPTMEN1KMT2AALDH1A1FTO | |
| SCHEMBL9134908 | 0.69 | FTO (0.67) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL9134914 | 0.69 | FTO (0.67) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL9136054 | 0.69 | FTO (0.67) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL9137315 | 0.69 | FTO (0.67) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL7988881 | 0.68 | FTO (0.47) | MAPTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9048939 | 0.67 | FTO (0.44) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820985-B1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-08-30 | — | — | EP | disclosed |
| EP-0820985-A1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-01-28 | — | — | EP | disclosed |