Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3591569 | 0.67 | — | — | |
| SCHEMBL15832528 | 0.60 | HDAC8 (0.30) | HDAC8 | |
| SCHEMBL997613 | 0.60 | HDAC8 (0.30) | HDAC8 | |
| SCHEMBL3088657 | 0.59 | — | — | |
| SCHEMBL17847641 | 0.58 | CRBN (0.31) | — | |
| SCHEMBL27154394 | 0.58 | — | — | |
| SCHEMBL4855499 | 0.58 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL796904 | 0.57 | HDAC8 (0.30) | HDAC8 | |
| SCHEMBL18894728 | 0.56 | — | — | |
| SCHEMBL28305401 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861255-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2000-06-28 | — | — | EP | claimed |
| US-6046197-A | NON-PEPTIDE AMIDE COMPOUNDS; STIMULATE HEMATOPOIESIS AND MAY BE USEFUL FOR TREATMENT OF VIRAL, FUNGAL AND BACTERIAL INFECTIOUS DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-04 | — | — | US | claimed |
| EP-0861255-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997018214-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | claimed |
| EP-0861255-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2000-06-28 | — | — | EP | disclosed |
| US-6046197-A | NON-PEPTIDE AMIDE COMPOUNDS; STIMULATE HEMATOPOIESIS AND MAY BE USEFUL FOR TREATMENT OF VIRAL, FUNGAL AND BACTERIAL INFECTIOUS DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-04 | — | — | US | disclosed |
| EP-0861255-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997018214-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |