Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099066 | 0.81 | CRBN (0.33) | CRBN | |
| SCHEMBL6032573 | 0.78 | — | — | |
| SCHEMBL19018320 | 0.67 | CRBN (0.32) | CRBN | |
| SCHEMBL20987249 | 0.63 | — | — | |
| SCHEMBL15547045 | 0.61 | — | — | |
| SCHEMBL7407751 | 0.61 | — | — | |
| SCHEMBL1137425 | 0.59 | MAPT (0.36) | CRBN | |
| SCHEMBL8137200 | 0.58 | HDAC8 (0.31) | — | |
| SCHEMBL30961504 | 0.55 | CRBN (0.32) | CRBN | |
| SCHEMBL5386997 | 0.54 | MAPT (0.59) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100166-A1 | SUBSTITUTED DIHYDRO-1H-PYRROLO[3,2-c]PYRIDIN-4(5H)-ONES AS RIPK3 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-06-23 | — | — | WO | disclosed |