Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523316 | 0.87 | NR1I2 (0.54) | NR1I2CYP3A4CYP2D6 | |
| Pleconaril SCHEMBL4656259 | 0.86 | NR1I2 (1.00) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8875401 | 0.86 | NR1I2 (0.84) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| Pleconaril SCHEMBL49383 | 0.86 | NR1I2 (1.00) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8130108 | 0.85 | NR1I2 (0.79) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL5099352 | 0.84 | NR1I2 (0.77) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL5099401 | 0.84 | NR1I2 (0.77) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8121315 | 0.83 | NR1I2 (0.76) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8120635 | 0.83 | NR1I2 (0.76) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8137086 | 0.83 | NR1I2 (0.76) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566199-B1 | 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | SANOFI SA (FR) | 2000-03-01 | — | — | EP | disclosed |
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5349068-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |