Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 3/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 12/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137204 | 0.87 | NR1I2 (0.74) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL9200266 | 0.84 | NR1I2 (0.73) | NR1I2CYP3A4CYP2D6IGF1RFGFR1 | |
| SCHEMBL9205929 | 0.83 | NR1I2 (0.57) | NR1I2CYP3A4CYP2D6S1PR1L3MBTL1 | |
| SCHEMBL9203587 | 0.82 | NR1I2 (0.56) | NR1I2CYP3A4CYP2D6S1PR1L3MBTL1 | |
| SCHEMBL9521718 | 0.81 | CYP3A4 (0.55) | NR1I2CYP3A4CYP2D6S1PR1L3MBTL1 | |
| SCHEMBL8136233 | 0.80 | CYP2D6 (0.66) | NR1I2CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL9521412 | 0.80 | NR1I2 (0.68) | NR1I2CYP3A4CYP2D6S1PR1L3MBTL1 | |
| SCHEMBL9202945 | 0.80 | NR1I2 (0.67) | NR1I2CYP3A4CYP2D6IGF1RFGFR1 | |
| SCHEMBL9520408 | 0.80 | NR1I2 (0.53) | NR1I2CYP3A4CYP2D6S1PR1L3MBTL1 | |
| SCHEMBL8875601 | 0.79 | CYP2D6 (0.53) | NR1I2CYP3A4CYP2D6S1PR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | claimed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | claimed |