Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.34 |
| ▸ | CCRL2 | O00421 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137219 | 1.00 | TRPV1 (0.34) | TRPV1CCRL2SCN9ACCR2KCNH2 | |
| SCHEMBL8137223 | 1.00 | TRPV1 (0.34) | TRPV1CCRL2SCN9ACCR2KCNH2 | |
| SCHEMBL8131535 | 0.93 | — | — | |
| SCHEMBL8131532 | 0.93 | — | — | |
| SCHEMBL8131533 | 0.93 | — | — | |
| SCHEMBL8123343 | 0.90 | — | — | |
| SCHEMBL8123346 | 0.90 | — | — | |
| SCHEMBL9588335 | 0.85 | ABCC9 (0.42) | — | |
| SCHEMBL9587527 | 0.85 | ABCC9 (0.42) | — | |
| SCHEMBL8084981 | 0.85 | ABCC9 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655448-B1 | BENZOPYRAN AND BENZOXAZINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5977167-A | Benzopyran and benzoxazine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5874446-A | ANTIASTHMATICS, ANTIEPILEPSY AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5614633-A | POTASSIUM CHANNEL ACTIVATOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0655448-A1 | BENZOPYRAN AND BENZOXAZINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-31 | — | — | EP | disclosed |