Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.65 |
| ▸ | CTSS | P25774 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245704 | 1.00 | CTSK (0.65) | CTSKCTSSCA1CA2 | |
| SCHEMBL29508370 | 1.00 | CTSK (0.65) | CTSKCTSSCA1CA2 | |
| SCHEMBL18109348 | 0.95 | CTSK (0.59) | CTSKCTSS | |
| SCHEMBL14820491 | 0.95 | CTSK (0.59) | CTSKCTSS | |
| SCHEMBL18109347 | 0.95 | CTSK (0.59) | CTSKCTSS | |
| SCHEMBL17614512 | 0.92 | CTSK (0.67) | CTSKCTSS | |
| SCHEMBL5040904 | 0.90 | CTSK (0.60) | CTSKCTSSCA1CA2 | |
| SCHEMBL18082612 | 0.90 | CTSK (0.60) | CTSKCTSSCA1CA2 | |
| SCHEMBL18130977 | 0.90 | CTSK (0.60) | CTSKCTSSCA1CA2 | |
| SCHEMBL2734195 | 0.90 | CTSK (0.59) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185831-A1 | STAT3 PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2022-06-16 | — | — | US | disclosed |
| US-6066672-A | OF GIVEN FORMULA COMPRISING A SUBSTITUTED AMINOALKYL(AMIDO OR ALKYLAMINO)ALKYL(AMIDO OR ALKYLAMINO)ALKYL(ALKENE, ALKYL OR ALKOXYCARBONYL) | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| EP-0882699-A1 | AMINO COMPOUNDS AND ANGIOTENSIN IV RECEPTOR AGONISTS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185831-A1 | STAT3 PROTEIN DEGRADERS | STAT3, JAK2, STAT5A | CTSK 2496/4885CTSS 1581/4885CA1 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.