SCHEMBL8137755

SCHEMBL8137755

Nc1cc(Oc2ccc(C(F)(F)F)c(Oc3ccc(C(F)(F)F)c(N)c3)c2)ccc1C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.45
L3MBTL1 Q9Y468 3/20 0.41
RAB9A P51151 1/20 0.41
AR P10275 16/20 0.40
MAPT P10636 2/20 0.38
LMNA P02545 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8137206 0.91 NR4A1 (0.44) NR4A1L3MBTL1RAB9AARMAPT
SCHEMBL8178499 0.91 NR4A1 (0.54) NR4A1L3MBTL1RAB9AARMAPT
SCHEMBL8145008 0.89 NR4A1 (0.45) NR4A1L3MBTL1RAB9AARMAPT
SCHEMBL8144441 0.89 NR4A1 (0.41) NR4A1L3MBTL1RAB9AARMAPT
SCHEMBL8138502 0.89 NR4A1 (0.39) NR4A1L3MBTL1RAB9AARMAPT
SCHEMBL8144954 0.89 NR4A1 (0.52) NR4A1L3MBTL1RAB9AARMAPT
SCHEMBL8146954 0.88 AR (0.43) NR4A1L3MBTL1RAB9AARMAPT
SCHEMBL8146088 0.87 NR4A1 (0.40) NR4A1L3MBTL1RAB9AARMAPT
SCHEMBL8139029 0.87 NR4A1 (0.40) NR4A1L3MBTL1RAB9AARMAPT
SCHEMBL8138439 0.86 L3MBTL1 (0.39) L3MBTL1RAB9AARMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9735429-B2 Lithium ion secondary battery HITACHI, LTD. (JP) 2017-08-15 US disclosed
EP-2858150-B1 LITHIUM ION SECONDARY BATTERY HITACHI LTD (JP) 2017-03-15 EP disclosed
US-20150155563-A1 LITHIUM ION SECONDARY BATTERY HITACHI, LTD., (JP) 2015-06-04 US disclosed
EP-2858150-A1 LITHIUM ION SECONDARY BATTERY Hitachi, Ltd. (JP) 2015-04-08 EP disclosed
US-6103860-A LOW DIELECTRIC CONSTANT, EXCELLENT TRANSPARENCY, LOW HYGROSCOPICITY AND EXCELLENT PROCESSABILITY; SUBSTRATE FOR AN OPTICAL DISK, A PICK-UP LENS, A PLASTIC SUBSTRATE FOR A LIQUID CELL AND A PRISM MITSUI CHEMICALS, INC. (JP) 2000-08-15 US disclosed
US-5990261-A Organic optical component MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0826717-A1 An organic optical component MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-03-04 EP disclosed