Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.63 |
| ▸ | PPARA | Q07869 | 11/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154817 | 0.93 | FFAR1 (0.60) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL8692244 | 0.84 | KDR (0.57) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL8694598 | 0.84 | KDR (0.59) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4848768 | 0.83 | FFAR1 (0.54) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL3278854 | 0.82 | MAPT (0.68) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL1067965 | 0.81 | MAOA (0.64) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8128837 | 0.81 | KDR (0.66) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL8130715 | 0.81 | FFAR1 (0.56) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL8130719 | 0.81 | FFAR1 (0.56) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL8122331 | 0.81 | KDR (0.56) | PPARGPPARAFFAR1KDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733631-B1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5723479-A | ANTILIPEMIC AGENTS AND ANTIGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0733631-A1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | Takeda Chemical Industries, Ltd. (JP) | 1996-09-25 | — | — | EP | disclosed |