SCHEMBL8139136

SCHEMBL8139136

C[C@H]1C[C@H](c2ccc(F)cc2)OC1=O

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.43
FADS1 O60427 5/20 0.42
KDM1A O60341 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17860841 0.84 MAPT (0.46) MAOB
SCHEMBL5936332 0.81 TSHR (0.43) MAOB
SCHEMBL18099888 0.81 TSHR (0.43) MAOB
SCHEMBL6288848 0.81 TSHR (0.43) MAOB
SCHEMBL11143204 0.76 MAOB (0.41) MAOBFADS1KDM1A
SCHEMBL641822 0.73 MEN1 (0.40) MAOBFADS1
SCHEMBL640280 0.72 MAOB (0.36) MAOBFADS1
SCHEMBL640279 0.72 MAOB (0.36) MAOBFADS1
SCHEMBL6288319 0.72 MGLL (0.35)
SCHEMBL21363715 0.70 KDM1A (0.39) MAOBFADS1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009008920-A2 HYDROXAMIC ACID DERIVATIVES OF 4-PHENYL 4-HYDROXY, 4-PHENYL 4-ALKOXY AND 4-PHENYL 4-ARYLALKOXY BUTYRIC ACID USEFUL AS THERAPEUTIC AGENTS FOR TREATING ANTHRAX POISONING PANTHERA BIOPHARMA, LLC. (US) 2009-01-15 WO disclosed