Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941957 | 0.82 | AKR1B1 (0.47) | MEN1KMT2APOLBAKR1B1PTGS1 | |
| SCHEMBL68391 | 0.79 | PTPN1 (0.46) | MEN1KMT2APOLBPTGS1PTPN1 | |
| SCHEMBL32667421 | 0.77 | MEN1 (1.00) | MEN1KMT2APOLBAKR1B1PTGS1 | |
| SCHEMBL3838235 | 0.76 | AKR1B1 (0.45) | MEN1KMT2APOLBAKR1B1PTGS1 | |
| SCHEMBL8464341 | 0.73 | POLB (0.50) | MEN1KMT2APOLBAKR1B1KDM4E | |
| SCHEMBL8464943 | 0.73 | POLB (0.54) | MEN1KMT2APOLBAKR1B1PTGS1 | |
| SCHEMBL8460501 | 0.73 | POLB (0.54) | MEN1KMT2APOLBAKR1B1PTPN1 | |
| SCHEMBL156238 | 0.72 | TYR (0.60) | MEN1KMT2APOLBAKR1B1EGFR | |
| SCHEMBL29419312 | 0.72 | TYR (0.60) | MEN1KMT2APOLBAKR1B1EGFR | |
| SCHEMBL3907285 | 0.72 | AKR1B1 (0.67) | MEN1KMT2APOLBAKR1B1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027155-A1 | METAL COMPLEXES SUITABLE FOR ATTACHMENT TO A SUPPORT AND SUPPORTED METAL COMPLEXES | The University Court of The University of St Andrews (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-2000006298-A1 | METAL COMPLEXES SUITABLE FOR ATTACHMENT TO A SUPPORT AND SUPPORTED METAL COMPLEXES | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2000-02-10 | — | — | WO | disclosed |