Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464943 | 0.90 | POLB (0.54) | POLBMEN1KMT2AAKR1B1EGFR | |
| SCHEMBL8464321 | 0.82 | KEAP1 (0.40) | AKR1B1CAMK2ACA2HPGDALDH1A1 | |
| SCHEMBL8460359 | 0.82 | TSHR (0.40) | POLBMEN1KMT2AAKR1B1TSHR | |
| SCHEMBL8462903 | 0.82 | AKR1B1 (0.36) | POLBMEN1KMT2AAKR1B1LMNA | |
| SCHEMBL8463501 | 0.82 | AKR1B1 (0.36) | POLBMEN1KMT2AAKR1B1CAMK2A | |
| SCHEMBL8459629 | 0.82 | HPGD (0.44) | POLBMEN1KMT2AAKR1B1HPGD | |
| SCHEMBL8460216 | 0.79 | POLB (0.42) | POLBMEN1KMT2AAKR1B1LMNA | |
| SCHEMBL8461777 | 0.77 | PTGS1 (0.57) | MEN1KMT2AAKR1B1LMNATSHR | |
| SCHEMBL8462477 | 0.77 | LCK (0.41) | POLBMEN1KMT2AAKR1B1HPGD | |
| SCHEMBL8464523 | 0.77 | HSD17B10 (0.56) | POLBCAMK2ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |