Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136478 | 0.90 | TLR7 (0.46) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL8126455 | 0.88 | TLR7 (0.45) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL8133004 | 0.86 | TLR7 (0.44) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL8135605 | 0.86 | TLR7 (0.47) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL8125963 | 0.86 | TLR7 (0.45) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL8135875 | 0.85 | TLR7 (0.43) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL8128022 | 0.85 | TLR7 (0.44) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL8132936 | 0.85 | TLR7 (0.46) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3866208 | 0.84 | TLR7 (0.56) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL8133750 | 0.84 | TLR7 (0.48) | TLR7TLR8LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |