Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135875 | 0.93 | TLR7 (0.43) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL8136478 | 0.91 | TLR7 (0.46) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL8126455 | 0.89 | TLR7 (0.45) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL14111995 | 0.89 | DRD4 (0.52) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3864117 | 0.88 | LMNA (0.46) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL8134654 | 0.88 | TLR7 (0.42) | TLR7MAP4K4LMNAPOLBHRH2 | |
| SCHEMBL8140138 | 0.85 | TLR7 (0.48) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3862412 | 0.84 | TLR7 (0.53) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3867357 | 0.84 | MCHR1 (0.49) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3862349 | 0.84 | TLR7 (0.47) | TLR7LMNAPOLBHRH2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |