Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CALML3 | P27482 | 1/20 | 0.45 |
| ▸ | SDHA | P31040 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156673 | 1.00 | MAOA (0.45) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8158245 | 0.89 | MAOA (0.42) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8135134 | 0.88 | MAOA (0.41) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8134838 | 0.85 | MAOA (0.39) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8133745 | 0.82 | MAOA (0.46) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8140841 | 0.81 | MAOA (0.43) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8131776 | 0.77 | MAOA (0.52) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL13298924 | 0.77 | MAOA (0.61) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8138685 | 0.76 | MAOA (0.41) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8553013 | 0.75 | MAOA (0.46) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005468-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010342-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1999-03-04 | — | — | WO | disclosed |