Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129993 | 0.88 | TAAR1 (0.66) | TAAR1ADRA1AHTR2AHTR2C | |
| Bromide SCHEMBL778334 | 0.86 | TAAR1 (0.64) | TAAR1ADRA1AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL3538524 | 0.86 | TAAR1 (0.64) | TAAR1ADRA1AHTR2AHTR2C | |
| SCHEMBL2934176 | 0.83 | KDM4E (0.48) | KDM4ETDP1 | |
| SCHEMBL8593783 | 0.81 | HTR2A (0.41) | TAAR1ADRA1AHTR2AHTR2C | |
| SCHEMBL1364667 | 0.80 | KDM4E (0.54) | TAAR1ADRA1AKDM4ETDP1 | |
| SCHEMBL3360919 | 0.80 | KDM4E (0.48) | KDM4ETDP1 | |
| SCHEMBL3356391 | 0.80 | KDM4E (0.48) | KDM4ETDP1 | |
| SCHEMBL28914589 | 0.80 | ADRA1A (0.51) | TAAR1ADRA1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14037603 | 0.79 | KDM4E (0.53) | KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037876-A1 | BIPHENYL DERIVATIVES AS PHARMACEUTICALS | Novartis AG (CH) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999023073-A1 | BIPHENYL DERIVATIVES AS PHARMACEUTICALS | NOVARTIS AG (CH) | 1999-05-14 | — | — | WO | disclosed |