Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 14/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 14/20 | 0.67 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758083 | 0.85 | CYP11B1 (0.68) | CYP11B1CYP11B2IDO1CYP19A1ALDH1A1 | |
| SCHEMBL7986619 | 0.84 | CYP11B1 (0.67) | CYP11B1CYP11B2IDO1CYP19A1 | |
| SCHEMBL765399 | 0.84 | CYP11B1 (0.67) | CYP11B1CYP11B2IDO1CYP19A1ALDH1A1 | |
| SCHEMBL7696780 | 0.84 | CYP11B1 (0.67) | CYP11B1CYP11B2IDO1CYP19A1ALDH1A1 | |
| SCHEMBL7700254 | 0.84 | CYP11B1 (0.67) | CYP11B1CYP11B2IDO1CYP19A1ALDH1A1 | |
| SCHEMBL7696643 | 0.83 | CYP11B1 (0.66) | CYP11B1CYP11B2IDO1CYP19A1ALDH1A1 | |
| SCHEMBL1757759 | 0.83 | CYP11B1 (0.66) | CYP11B1CYP11B2IDO1CYP19A1ALDH1A1 | |
| SCHEMBL8135755 | 0.83 | CYP11B1 (0.65) | CYP11B1CYP11B2IDO1ALDH1A1 | |
| SCHEMBL5935193 | 0.81 | CYP11B1 (0.63) | CYP11B1CYP11B2IDO1CYP19A1FNTA | |
| SCHEMBL8133106 | 0.81 | CYP11B1 (0.63) | CYP11B1CYP11B2IDO1CYP19A1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054882-A1 | CONDENSED HETEROCYCLIC SYSTEM DERIVATIVES, PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041248-A1 | CONDENSED HETEROCYCLIC SYSTEM DERIVATIVES, PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 1999-08-19 | — | — | WO | disclosed |