Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 4/20 | 0.33 |
| ▸ | ATP4B | P51164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358560 | 0.76 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL10518733 | 0.66 | CA1 (0.36) | CYP3A4CYP1A2CYP2C19TP53MAPT | |
| SCHEMBL7499341 | 0.65 | CYP3A4 (1.00) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL13176306 | 0.65 | CYP1A2 (0.58) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6350752 | 0.65 | CYP3A4 (0.69) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6356148 | 0.63 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6351485 | 0.62 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL7216941 | 0.62 | CYP3A4 (0.81) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL28749509 | 0.62 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL14685219 | 0.61 | CYP1A2 (0.42) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683780-B1 | IMIDAZOPYRIDINES AND THEIR USE IN TREATING GASTROINTESTINAL DISEASES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0683780-A1 | IMIDAZOPYRIDINES AND THEIR USE IN TREATING GASTROINTESTINAL DISEASES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994018199-A1 | IMIDAZOPYRIDINES AND THEIR USE IN TREATING GASTROINTESTINAL DISEASES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-08-18 | — | — | WO | disclosed |