Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | PNP | P00491 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furafylline SCHEMBL191214 | 0.81 | MEN1 (1.00) | MEN1KMT2ALMNACYP1A1CYP1A2 | |
| SCHEMBL4624542 | 0.80 | PNP (0.60) | MEN1KMT2ABLMTSHRPNP | |
| SCHEMBL6346663 | 0.74 | ADORA2A (0.59) | MEN1KMT2ALMNACYP1A1CYP1A2 | |
| SCHEMBL10963141 | 0.73 | ADORA2A (0.55) | MEN1KMT2ALMNABLMSMN1; SMN2 | |
| SCHEMBL8128166 | 0.72 | MEN1 (0.67) | MEN1KMT2ALMNACYP1A1CYP1A2 | |
| SCHEMBL8143264 | 0.72 | MEN1 (0.67) | MEN1KMT2ALMNACYP1A1CYP1A2 | |
| SCHEMBL8128164 | 0.72 | MEN1 (0.67) | MEN1KMT2ALMNACYP1A1CYP1A2 | |
| SCHEMBL8135676 | 0.70 | TSHR (0.62) | MEN1KMT2ALMNACYP1A1CYP1A2 | |
| SCHEMBL10979332 | 0.70 | ADORA2A (0.41) | MEN1KMT2ALMNACYP1A1CYP1A2 | |
| SCHEMBL5646 | 0.70 | PDE2A (0.61) | MEN1KMT2ALMNAMAPK1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075029-A | Xanthine modulators of metabolism of cellular P-450 | CELL THERAPEUTICS, INC. (US) | 2000-06-13 | — | — | US | disclosed |