SCHEMBL8143197

SCHEMBL8143197

O=C1OCCN1CNc1ccc2c(c1)OCc1nccn1-2

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.40
LTA4H P09960 1/20 0.30
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8125926 0.68 F10 (0.41) F10
SCHEMBL87094 0.68 F10 (0.39) F10
SCHEMBL12188619 0.67 F10 (0.39) F10
SCHEMBL426379 0.67 ALDH1A1 (0.41) F10
SCHEMBL429806 0.65 F10 (0.39) F10
SCHEMBL12169227 0.65 F10 (0.37) F10
SCHEMBL10090615 0.65 F10 (0.37) F10
SCHEMBL432928 0.64 GRM5 (0.43) F10
Hydrochloric Acid SCHEMBL8143975 0.63 F10 (0.63) F10
SCHEMBL18013298 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054889-A1 NEW OXAZOLIDINONES WITH AZOL-CONTAINING TRICYCLES Bayer Aktiengesellschaft (DE) 2000-11-29 EP disclosed
WO-1999040094-A1 AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS BAYER AKTIENGESELLSCHAFT (DE) 1999-08-12 WO disclosed