Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151552 | 0.85 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL23440033 | 0.84 | F2 (0.60) | CYP1A2CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL8144393 | 0.82 | PTPN1 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL8143584 | 0.82 | KMT2A (0.76) | CYP2D6CYP2C19KMT2ACA12CA9 | |
| SCHEMBL8143252 | 0.82 | KMT2A (0.53) | KMT2AMEN1CA12CA9MAPT | |
| SCHEMBL9323617 | 0.81 | KMT2A (0.73) | CYP1A2CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL8871694 | 0.80 | KMT2A (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL6967373 | 0.79 | TDP1 (0.51) | CYP1A2KMT2AMEN1CA12CA9 | |
| SCHEMBL8872105 | 0.78 | KMT2A (0.47) | KMT2AMEN1CA12CA9 | |
| SCHEMBL8134728 | 0.78 | USP2 (0.52) | CYP1A2CYP3A4CYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040326-A | 3-deoxyglucosone production inhibitor | NIPPON ZOKI PHARMACEUTICALS CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0855182-A1 | 3-Deoxyglucosone production inhibitor | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| EP-0353198-B1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-4985453-A | DIABETES TREATMENT | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0353198-A1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-01-31 | — | — | EP | disclosed |