Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325767 | 0.83 | KMT2A (0.77) | KMT2APTGS1PTGS2MAPTMEN1 | |
| SCHEMBL8143249 | 0.82 | CYP1A2 (0.61) | KMT2AMAPTCA12CA9MEN1 | |
| SCHEMBL8134728 | 0.81 | USP2 (0.52) | KMT2AKDM4EMEN1 | |
| SCHEMBL6967373 | 0.79 | TDP1 (0.51) | KMT2AMAPTCA12CA9KDM4E | |
| SCHEMBL8143584 | 0.79 | KMT2A (0.76) | KMT2AMAPTCA12CA9POLB | |
| SCHEMBL8872105 | 0.78 | KMT2A (0.47) | KMT2ACA12CA9KDM4EMEN1 | |
| SCHEMBL8143224 | 0.77 | ACHE (0.47) | KMT2ACA12CA9ALDH1A1 | |
| SCHEMBL8150342 | 0.75 | MAPT (0.68) | KMT2AMAPTMEN1LMNAALDH1A1 | |
| SCHEMBL8871694 | 0.74 | KMT2A (0.46) | KMT2AMAPTCA12CA9RAB9A | |
| SCHEMBL21043993 | 0.72 | KMT2A (0.63) | KMT2AMAPTKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040326-A | 3-deoxyglucosone production inhibitor | NIPPON ZOKI PHARMACEUTICALS CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0855182-A1 | 3-Deoxyglucosone production inhibitor | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| EP-0353198-B1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-4985453-A | DIABETES TREATMENT | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0353198-A1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-01-31 | — | — | EP | disclosed |