Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27383131 | 0.91 | DGAT1 (0.35) | NPSR1DGAT1 | |
| SCHEMBL7874343 | 0.87 | CYP4F2 (0.30) | NPSR1CYP4F2CYP4A11 | |
| SCHEMBL26108087 | 0.87 | CYP4F2 (0.30) | NPSR1CYP4F2CYP4A11 | |
| SCHEMBL7333852 | 0.85 | — | — | |
| SCHEMBL4590196 | 0.83 | — | — | |
| SCHEMBL7313574 | 0.81 | CYP4F2 (0.31) | CYP4F2CYP4A11 | |
| SCHEMBL11306523 | 0.76 | — | — | |
| SCHEMBL7488055 | 0.75 | CYP4F2 (0.30) | CYP4F2CYP4A11 | |
| SCHEMBL8156937 | 0.75 | CHRM2 (0.33) | — | |
| SCHEMBL8144169 | 0.75 | CHRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |