SCHEMBL8145138

SCHEMBL8145138

[NH]C(=O)CCCCCCCCCCCN

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.59
THRB P10828 2/20 0.59
KMT2A Q03164 2/20 0.59
MEN1 O00255 1/20 0.59
ALDH1A1 P00352 1/20 0.59
PLG P00747 1/20 0.59
ALOX15 P16050 1/20 0.59
SLC6A2 P23975 1/20 0.59
RECQL P46063 1/20 0.59
SLC6A3 Q01959 1/20 0.59
PAOX Q6QHF9 4/20 0.56
NFKB1 P19838 3/20 0.55
CYP2D6 P10635 1/20 0.55
BLM P54132 3/20 0.52
NPSR1 Q6W5P4 2/20 0.52
TSHR P16473 3/20 0.44
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA3 P07451 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5840397 1.00 LMNA (0.59) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL4287392 1.00
SCHEMBL7769328 1.00 LMNA (0.59) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL4292947 0.97
SCHEMBL2215091 0.88
SCHEMBL4740198 0.85 TSHR (0.47) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL9282620 0.80 KMT2A (0.43) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL10665172 0.78 LMNA (0.36) LMNATHRBKMT2AMEN1ALDH1A1
Aminocaproic Acid SCHEMBL15401288 0.78 LMNA (0.94) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL152548 0.77 LMNA (0.65) LMNATHRBKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017906-A Polyamine conjugates for treatment of infection INTERCARDIA, INC. (US) 2000-01-25 US disclosed
US-5795870-A STEROID RING WITH AMINE GROUP SIDE CHAINS TRUSTEES OF PRINCETON UNIVERSITY (US) 1998-08-18 US disclosed
US-5780444-A EXOGENOUS OR ENDOGENOUS NUCLEIC ACID IS CONTACTED WITH THE CELL IN THE PRESENCE OF A POLYHYDROXYLATED OR POLYGLYCOSYLATED BILE ACID DERIVATIZED WITH AN AMINE-CONTAINING SIDE CHAIN AND A FUSOGENIC LIPID TRUSTEES OF PRINCETON UNIVERSITY (US) 1998-07-14 US disclosed
US-5744453-A Polyamine conjugates for treatment of infection MINTZ CLIFFORD S (US) 1998-04-28 US disclosed
EP-0756601-A1 COMPOSITIONS AND METHODS FOR CELL TRANSFORMATION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1997-02-05 EP disclosed
WO-1995029186-A1 COMPOSITIONS AND METHODS FOR CELL TRANSFORMATION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1995-11-02 WO disclosed