Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8134506 | 1.00 | TRPV1 (0.42) | TRPV1ALDH1A1MMEACECPA1 | |
| SCHEMBL28905054 | 1.00 | TRPV1 (0.42) | TRPV1ALDH1A1MMEACECPA1 | |
| SCHEMBL8144552 | 1.00 | TRPV1 (0.42) | TRPV1ALDH1A1MMEACECPA1 | |
| SCHEMBL8437041 | 1.00 | TRPV1 (0.42) | TRPV1ALDH1A1MMEACECPA1 | |
| SCHEMBL8247672 | 1.00 | TRPV1 (0.42) | TRPV1ALDH1A1MMEACECPA1 | |
| SCHEMBL8145356 | 1.00 | TRPV1 (0.42) | TRPV1ALDH1A1MMEACECPA1 | |
| SCHEMBL4401773 | 0.81 | TRPV1 (0.44) | TRPV1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20404606 | 0.80 | TRPV1 (0.42) | TRPV1ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6729274 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL6729268 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118849-A2 | HIV-1 PROTEASE INHIBITORS | UNIVERSITY OF MASSACHUSETTS (US) | 2008-10-02 | — | — | WO | disclosed |