Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666237 | 0.85 | PTPN1 (0.60) | PTPN1NR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL689994 | 0.85 | PTPN1 (0.60) | PTPN1NR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL29600450 | 0.81 | NR4A1 (0.68) | PTPN1NR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL71960 | 0.81 | NR4A1 (0.68) | PTPN1NR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL9668753 | 0.81 | NR4A1 (0.53) | PTPN1NR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL30367135 | 0.79 | PTPN1 (0.66) | PTPN1NR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL71261 | 0.79 | PTPN1 (0.66) | PTPN1NR4A1NR4A2NR4A3CDC25B | |
| Hydrochloric Acid SCHEMBL4607125 | 0.79 | PTPN1 (0.66) | PTPN1NR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL2708593 | 0.79 | PTPN1 (0.53) | PTPN1NR4A1NR4A2NR4A3CDC25B | |
| Hydrochloric Acid SCHEMBL6847145 | 0.77 | PTPN1 (0.63) | PTPN1NR4A1NR4A2NR4A3CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735019-B1 | Retroviral protease inhibitors | MONSANTO CO (US) | 2000-09-20 | — | — | EP | disclosed |
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |