SCHEMBL7666237

SCHEMBL7666237

N#Cc1ccc2c(C(=O)O)cccc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.60
NR4A1 P22736 1/20 0.55
NR4A2 P43354 1/20 0.55
NR4A3 Q92570 1/20 0.55
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
XDH P47989 2/20 0.50
SLC22A12 Q96S37 2/20 0.50
HTT P42858 2/20 0.49
CDC25B P30305 2/20 0.45
GRIN2D O15399 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
NOTUM Q6P988 1/20 0.43
TBXAS1 P24557 1/20 0.43
ALB P02768 1/20 0.42
F2 P00734 1/20 0.42
PLG P00747 1/20 0.42
PLAU P00749 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12212889 0.88 NR4A1 (0.56) PTPN1NR4A1NR4A2NR4A3CA1
SCHEMBL7671173 0.85 CA1 (0.54) PTPN1CA1CA2XDHSLC22A12
SCHEMBL8145254 0.85 PTPN1 (0.62) PTPN1NR4A1NR4A2NR4A3XDH
SCHEMBL689994 0.83 PTPN1 (0.60) PTPN1NR4A1NR4A2NR4A3CDC25B
SCHEMBL7668730 0.83 XDH (0.46) PTPN1CA1CA2XDHSLC22A12
SCHEMBL7672321 0.81 CA1 (0.46) CA1CA2PLAUALDH1A1MAPT
SCHEMBL17288524 0.81 CA1 (0.49) PTPN1CA1CA2XDHSLC22A12
SCHEMBL756422 0.81 XDH (0.62) PTPN1NR4A1NR4A2NR4A3CA1
SCHEMBL29600450 0.80 NR4A1 (0.68) PTPN1NR4A1NR4A2NR4A3CDC25B
SCHEMBL71960 0.80 NR4A1 (0.68) PTPN1NR4A1NR4A2NR4A3CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110250509-A1 SECONDARY BATTERY AND ELECTRONIC DEVICE SONY CORPORATION (JP) 2011-10-13 US disclosed
US-20110250509-A1 SECONDARY BATTERY AND ELECTRONIC DEVICE SONY CORPORATION (JP) 2011-10-13 US disclosed
US-6365602-B1 FOR THERAPY OF DEPRESSION, ANXIETY, ASTHMA, PAIN, INFLAMMATION, URINARY INCONTINENCE AND OTHER DISEASE CONDITIONS ASTRA ZENECA AB (SE) 2002-04-02 US disclosed
EP-1097137-A1 N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS AstraZeneca AB (SE) 2001-05-09 EP disclosed
WO-2000002859-A1 N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS ASTRAZENECA AB (SE) 2000-01-20 WO disclosed
WO-1995033745-A9 NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY 1996-01-18 WO disclosed
WO-1995033745-A2 NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY SRI INTERNATIONAL (US) 1995-12-14 WO disclosed