Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492401 | 0.82 | CYP19A1 (0.34) | CYP19A1ERN1ELANECTSGSIGMAR1 | |
| SCHEMBL16317134 | 0.73 | — | — | |
| SCHEMBL8151965 | 0.71 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL14420341 | 0.71 | HTR2C (0.41) | ELANECTSG | |
| SCHEMBL5497614 | 0.70 | CYP19A1 (0.34) | CYP19A1ERN1SIGMAR1 | |
| SCHEMBL5497620 | 0.70 | CYP19A1 (0.34) | CYP19A1ERN1SIGMAR1 | |
| SCHEMBL7007402 | 0.70 | CYP19A1 (0.42) | CYP19A1ERN1ELANECTSGSIGMAR1 | |
| SCHEMBL8152835 | 0.69 | CYP19A1 (0.58) | CYP19A1ERN1SIGMAR1 | |
| SCHEMBL13863146 | 0.69 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL18767673 | 0.68 | SIGMAR1 (0.30) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098368-A1 | INHIBITORS OF HEPATITIS C NS3 PROTEASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-21 | — | — | WO | disclosed |