SCHEMBL8145506

SCHEMBL8145506

Nc1c(F)ccc(Oc2cc(Oc3ccc(F)c(N)c3F)c(C(F)(F)F)c(C(F)(F)F)c2F)c1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8147724 0.91 L3MBTL1 (0.32) RAB9AL3MBTL1
SCHEMBL8144359 0.90 L3MBTL1 (0.33) RAB9AL3MBTL1
SCHEMBL8145118 0.82 L3MBTL1 (0.35) RAB9AL3MBTL1
SCHEMBL8147919 0.82 KDM4E (0.30) RAB9AL3MBTL1
SCHEMBL8146763 0.82 KDM4E (0.30) RAB9AL3MBTL1
SCHEMBL8151584 0.81
SCHEMBL8146625 0.81 MPL (0.35) RAB9AL3MBTL1
SCHEMBL8143568 0.80 HTR2A (0.30)
SCHEMBL8137948 0.80 AR (0.36) RAB9AL3MBTL1
SCHEMBL8145091 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103860-A LOW DIELECTRIC CONSTANT, EXCELLENT TRANSPARENCY, LOW HYGROSCOPICITY AND EXCELLENT PROCESSABILITY; SUBSTRATE FOR AN OPTICAL DISK, A PICK-UP LENS, A PLASTIC SUBSTRATE FOR A LIQUID CELL AND A PRISM MITSUI CHEMICALS, INC. (JP) 2000-08-15 US disclosed
US-5990261-A Organic optical component MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0826717-A1 An organic optical component MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-03-04 EP disclosed