Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034075 | 0.91 | KMT2A (0.55) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL20204699 | 0.87 | MEN1 (0.44) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL20204676 | 0.82 | MEN1 (0.41) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL20201643 | 0.81 | MEN1 (0.40) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL18183389 | 0.78 | MEN1 (0.38) | MEN1KMT2AALDH1A1THRB | |
| SCHEMBL9769271 | 0.77 | GBA1 (0.47) | GNAI3GNAO1GNAI1GBA1ALOX5 | |
| SCHEMBL31093244 | 0.77 | GBA1 (0.47) | GNAI3GNAO1GNAI1GBA1ALOX5 | |
| SCHEMBL9769185 | 0.77 | GBA1 (0.47) | GNAI3GNAO1GNAI1GBA1ALOX5 | |
| SCHEMBL31093212 | 0.77 | GBA1 (0.47) | GNAI3GNAO1GNAI1GBA1ALOX5 | |
| SCHEMBL9617015 | 0.77 | GBA1 (0.47) | GNAI3GNAO1GNAI1GBA1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025496-A | Process for preparing heterocyclic carbenes | CELANESE GMBH (DE) | 2000-02-15 | — | — | US | disclosed |
| EP-0888308-A1 | PROCESS FOR PREPARING HETEROCYCLIC CARBENES | Celanese GmbH (DE) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034875-A1 | PROCESS FOR PREPARING HETEROCYCLIC CARBENES | CELANESE GMBH (DE) | 1997-09-25 | — | — | WO | disclosed |