Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146239 | 0.87 | MEN1 (0.47) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL22972986 | 0.85 | MEN1 (0.35) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL8034075 | 0.82 | KMT2A (0.55) | MEN1KMT2AALDH1A1GAATHRB | |
| SCHEMBL20204676 | 0.79 | MEN1 (0.41) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL4398429 | 0.78 | — | — | |
| SCHEMBL20201643 | 0.77 | MEN1 (0.40) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL4421020 | 0.75 | GBA1 (0.41) | GNAI3GNAO1GNAI1ALDH1A1GAA | |
| SCHEMBL18603297 | 0.74 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL24420748 | 0.73 | GNAI3 (0.41) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL10721244 | 0.73 | GBA1 (0.44) | GNAI3GNAO1GNAI1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |