Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154453 | 0.82 | MCHR1 (0.49) | MCHR1CYP2D6KCNH2 | |
| SCHEMBL8154457 | 0.82 | MCHR1 (0.49) | MCHR1CYP2D6KCNH2 | |
| SCHEMBL782565 | 0.82 | MCHR1 (0.49) | MCHR1CYP2D6KCNH2 | |
| SCHEMBL8141837 | 0.82 | MAPT (0.31) | MAPTHRH3 | |
| Fumaric Acid SCHEMBL8146701 | 0.73 | KMT2A (0.43) | MCHR1KCNH2 | |
| Fumaric Acid SCHEMBL8155294 | 0.70 | HRH4 (0.40) | MAPTBAZ2BMCHR1KCNH2HRH3 | |
| Fumaric Acid SCHEMBL8373626 | 0.70 | HRH4 (0.40) | MAPTBAZ2BMCHR1KCNH2HRH3 | |
| SCHEMBL8372824 | 0.70 | MCHR1 (0.38) | MAPTHSD17B10MCHR1 | |
| SCHEMBL1988850 | 0.68 | SIGMAR1 (0.67) | — | |
| SCHEMBL12868041 | 0.65 | BAZ2B (0.56) | MAPTBAZ2BHSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063803-A | ANALGESICS AND CHEMICAL INTERMEDIATES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-05-16 | — | — | US | disclosed |