Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.56 |
| ▸ | HTR2C | P28335 | 11/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148467 | 0.90 | HTR2A (0.56) | HTR2AHTR2CKCNH2OPRL1ALDH1A1 | |
| SCHEMBL8154321 | 0.88 | HTR2A (0.53) | HTR2AHTR2CKCNH2 | |
| SCHEMBL8153366 | 0.87 | HTR2A (0.56) | HTR2AHTR2CKCNH2OPRL1IDO1 | |
| SCHEMBL8146275 | 0.86 | HTR2A (0.52) | HTR2AHTR2CKCNH2OPRL1 | |
| SCHEMBL22201819 | 0.86 | HTR2A (0.52) | HTR2AHTR2CKCNH2OPRL1KDM4E | |
| SCHEMBL8145957 | 0.85 | HTR2A (0.51) | HTR2AHTR2CKCNH2OPRL1 | |
| SCHEMBL8152477 | 0.85 | HTR2A (0.51) | HTR2AHTR2CKCNH2OPRL1 | |
| SCHEMBL8146883 | 0.84 | HTR2A (0.43) | HTR2AHTR2COPRL1 | |
| SCHEMBL16191075 | 0.83 | HTR2A (0.58) | HTR2AHTR2CKCNH2OPRL1KDM4E | |
| SCHEMBL10991278 | 0.83 | HTR2A (0.42) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36849-E | 2-(4-(ALK(EN)YL, ALKOXY, ALKANOYL)-4'-BICYCLOHEXYL)-1-(2,3-(HALO OR NITRILE),4-HALOPHENYL)ETHANE COMPOUNDS; ELECTROOPTICAL DISPLAY WITH MULTIPLEX OPERATION COMPRISING A LIQUID CRYSTAL MIXTURE AS DIELECTRIC | MERCK PATENT GMBH (DE) | 2000-09-05 | — | — | US | claimed |
| US-RE36849-E | 2-(4-(ALK(EN)YL, ALKOXY, ALKANOYL)-4'-BICYCLOHEXYL)-1-(2,3-(HALO OR NITRILE),4-HALOPHENYL)ETHANE COMPOUNDS; ELECTROOPTICAL DISPLAY WITH MULTIPLEX OPERATION COMPRISING A LIQUID CRYSTAL MIXTURE AS DIELECTRIC | MERCK PATENT GMBH (DE) | 2000-09-05 | — | — | US | disclosed |
| US-4710315-A | USE WITH MULTIPLEXIBLE DISPLAYS HAVING HIGH DENSITY IMAGES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-12-01 | — | — | US | disclosed |