Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amantadine SCHEMBL15013442 | 0.76 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL3364005 | 0.76 | GRIN2D (0.48) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3363998 | 0.76 | GRIN2D (0.48) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30792923 | 0.74 | HSD11B1 (0.52) | KDM4EHPGDKMT2ANPC1RAB9A | |
| SCHEMBL17995255 | 0.74 | HSD11B1 (0.52) | KDM4EHPGDKMT2ANPC1RAB9A | |
| SCHEMBL12460834 | 0.73 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL813918 | 0.73 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL813985 | 0.72 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5212985 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL6852240 | 0.71 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603957-B1 | POLYMERISATION AND OLIGOMERISATION CATALYSTS | INEOS SALES UK LTD (GB) | 2015-10-28 | — | — | EP | disclosed |
| EP-1789459-B1 | POLYOLEFINS | INEOS SALES UK LTD (GB) | 2014-04-30 | — | — | EP | disclosed |
| US-8067328-B2 | Polymerisation and oligomerisation catalysts | INEOS EUROPE LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |
| US-7989565-B2 | Polyolefins | INEOS EUROPE LIMITED (GB) | 2011-08-02 | — | — | US | disclosed |
| US-7989565-B2 | Polyolefins | INEOS EUROPE LIMITED (GB) | 2011-08-02 | — | — | US | disclosed |
| US-20090124487-A1 | Polyolefins | BARCLAYS BANK PLC (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124487-A1 | Polyolefins | BARCLAYS BANK PLC (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20070207918-A1 | Polymerisation and Oligomerisation Catalysts | INEOS SALES (UK) LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
| US-20070207918-A1 | Polymerisation and Oligomerisation Catalysts | INEOS SALES (UK) LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |