SCHEMBL8147304

SCHEMBL8147304

Cc1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(OCC(C)C)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADK P55263 17/20 0.64
SRC P12931 2/20 0.43
ABL1 P00519 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8153484 0.86 ADK (0.83) ADK
SCHEMBL7973088 0.86 ADK (0.65) ADK
SCHEMBL7973176 0.85 ADK (0.77) ADK
SCHEMBL7974905 0.83 ADK (0.62) ADK
SCHEMBL7974874 0.82 ADK (0.77) ADK
SCHEMBL7971463 0.82 ADK (0.67) ADK
SCHEMBL7961521 0.82 ADK (0.67) ADK
SCHEMBL7961439 0.81 ADK (0.65) ADK
SCHEMBL7974716 0.81 ADK (0.76) ADK
SCHEMBL7971457 0.81 ADK (0.71) ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0979230-A1 6,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS Abbott Laboratories (US) 2000-02-16 EP claimed
WO-1998046603-A1 6,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS ABBOTT LABORATORIES (US) 1998-10-22 WO claimed
EP-0979230-A1 6,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS Abbott Laboratories (US) 2000-02-16 EP disclosed
WO-1998046603-A1 6,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS ABBOTT LABORATORIES (US) 1998-10-22 WO disclosed