Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.49 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 4/20 | 0.44 |
| ▸ | FNTB | P49356 | 4/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157864 | 0.88 | GABBR2 (0.45) | GABBR2GABBR1CYP2C9MEN1KMT2A | |
| SCHEMBL13302695 | 0.85 | GABBR2 (0.45) | GABBR2GABBR1CYP2C9MEN1KMT2A | |
| SCHEMBL13302650 | 0.85 | GABBR2 (0.42) | GABBR2GABBR1CYP2C9MEN1KMT2A | |
| SCHEMBL13324051 | 0.84 | GABBR2 (0.41) | GABBR2GABBR1CYP2C9MEN1KMT2A | |
| SCHEMBL2231735 | 0.80 | GABBR2 (0.49) | GABBR2GABBR1CYP2C9MEN1KMT2A | |
| SCHEMBL2231634 | 0.80 | GABBR2 (0.51) | GABBR2GABBR1CYP2C9MEN1KMT2A | |
| SCHEMBL637735 | 0.80 | ATM (0.59) | GABBR2GABBR1CYP2C9MEN1KMT2A | |
| SCHEMBL1998566 | 0.80 | ATM (0.59) | GABBR2GABBR1CYP2C9MEN1KMT2A | |
| SCHEMBL2230680 | 0.79 | GABBR2 (0.54) | GABBR2GABBR1CYP2C9MEN1KMT2A | |
| SCHEMBL2231575 | 0.79 | GABBR2 (0.48) | GABBR2GABBR1CYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100145057-A1 | NOVEL PRODRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2010-06-10 | — | — | US | disclosed |
| US-20100145057-A1 | NOVEL PRODRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2010-06-10 | — | — | US | disclosed |
| WO-2008111096-A2 | NOVEL PRODRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145057-A1 | NOVEL PRODRUGS | UGT2B7, UGT1A1, UGT1A6 | GABBR2 2249/4885GABBR1 2117/4885CYP2C9 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.