Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.85 |
| ▸ | FNTB | P49356 | 19/20 | 0.85 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.76 |
| ▸ | NRAS | P01111 | 1/20 | 0.52 |
| ▸ | HRAS | P01112 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147508 | 1.00 | FNTA (0.85) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL31472012 | 0.92 | FNTA (1.00) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL445940 | 0.90 | FNTA (0.88) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL445938 | 0.90 | FNTA (0.88) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL31472009 | 0.89 | FNTA (0.68) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL9083203 | 0.89 | FNTA (0.87) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL9083210 | 0.89 | FNTA (0.87) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL31471978 | 0.87 | FNTA (0.80) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL445627 | 0.86 | FNTA (1.00) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL31472029 | 0.86 | FNTA (1.00) | FNTAFNTBPGGT1BNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060038-A | Radiolabeled farnesyl-protein transferase inhibitors | MERCK & CO., INC. (US) | 2000-05-09 | — | — | US | disclosed |