SCHEMBL31472012

SCHEMBL31472012

CCCCC1CN(c2cccc(Cl)c2)C(=O)CN1Cc1cncn1Cc1ccc(C#N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 19/20 1.00
FNTB P49356 18/20 1.00
PGGT1B P53609 5/20 0.74
NRAS P01111 1/20 0.64
HRAS P01112 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8147487 0.92 FNTA (0.85) FNTAFNTBPGGT1BNRASHRAS
SCHEMBL8147508 0.92 FNTA (0.85) FNTAFNTBPGGT1BNRASHRAS
SCHEMBL31471953 0.92 FNTA (0.85) FNTAFNTBPGGT1BNRASHRAS
SCHEMBL3499935 0.91 FNTA (0.84) FNTAFNTBPGGT1BNRASHRAS
SCHEMBL3499938 0.91 FNTA (0.84) FNTAFNTBPGGT1BNRASHRAS
Hydrochloric Acid SCHEMBL9083873 0.91 FNTA (0.83) FNTAFNTBPGGT1BNRASHRAS
Hydrochloric Acid SCHEMBL9083888 0.91 FNTA (0.83) FNTAFNTBPGGT1BNRASHRAS
SCHEMBL8006490 0.90 FNTA (0.86) FNTAFNTBPGGT1BNRASHRAS
SCHEMBL3500214 0.90 FNTA (0.86) FNTAFNTBPGGT1BNRASHRAS
SCHEMBL3501295 0.90 FNTA (0.82) FNTAFNTBPGGT1BNRASHRAS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250114350-A1 INHIBITORS OF PRENYLTRANSFERASES AS ANTIFUNGAL AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2025-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250114350-A1 INHIBITORS OF PRENYLTRANSFERASES AS ANTIFUNGAL AGENTS FNTA, FNTB, FDPS FNTA 1/4885FNTB 2/4885PGGT1B 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.