Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597515 | 0.87 | POLB (0.56) | POLBKDM4EKMT2AL3MBTL1MAPK1 | |
| SCHEMBL6598175 | 0.82 | POLB (0.73) | POLBKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8145490 | 0.79 | POLB (0.56) | POLBKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL272817 | 0.77 | POLB (0.65) | POLBKDM4EKMT2AL3MBTL1MAPK1 | |
| SCHEMBL8141825 | 0.76 | POLB (0.52) | POLBKDM4EKMT2AL3MBTL1MAPK1 | |
| SCHEMBL6595989 | 0.75 | HSD17B10 (0.61) | POLBKDM4EKMT2AALDH1A1NLRP3 | |
| SCHEMBL29824483 | 0.74 | KMT2A (0.56) | POLBKMT2ALMNA | |
| SCHEMBL7168499 | 0.74 | KMT2A (0.56) | POLBKMT2ALMNA | |
| SCHEMBL7886074 | 0.71 | HSD17B10 (0.51) | POLBKDM4EKMT2AALDH1A1NLRP3 | |
| SCHEMBL28563448 | 0.70 | MYC (0.36) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127076-A | ELECTROPHOTOSENSITIVE MATERIAL CONTAINING NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE DERIVATIVE AS ELECTRON TRANSPORTING AGENT | KYOCERA MITA CORPORATION (JP) | 2000-10-03 | — | — | US | disclosed |
| EP-0962458-A1 | New naphthalenetetracarboxylic acid diimides as electron transporting agents in photosensitive material for electrophotography | MITA INDUSTRIAL CO. LTD. (JP) | 1999-12-08 | — | — | EP | disclosed |