SCHEMBL28563448

SCHEMBL28563448

COC(C)c1cccc(C)c1-c1cc(C(N)=O)c2c(C(=O)O)ccc(C(=O)O)c2c1C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.36
TYMS P04818 1/20 0.33
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
CYP1A2 P05177 1/20 0.30
AKR1C2 P52895 1/20 0.30
AKR1C1 Q04828 1/20 0.30
FABP4 P15090 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28913018 0.82 CA12 (0.40) MYCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL28565883 0.79 TTR (0.40) MYCKDM4EHSD17B10CYP1A2
SCHEMBL28559363 0.78 MYC (0.40) MYCTYMSKDM4EALDH1A1HPGD
SCHEMBL28776459 0.71 CYP1A2 (0.48) MYCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL28632785 0.71 MYC (0.46) MYCTYMSKDM4EALDH1A1HPGD
SCHEMBL28574564 0.70 KDM4E (0.35) MYCKDM4ECYP1A2
SCHEMBL28016040 0.70 ACE2 (0.39) MYCHSD17B10CYP1A2FABP4
SCHEMBL8147647 0.70 POLB (0.51) KDM4EALDH1A1HSD17B10
SCHEMBL28391558 0.70 ACE2 (0.38) MYCHSD17B10CYP1A2FABP4
SCHEMBL28864212 0.68 PLA2G2A (0.53) KDM4ECYP1A2AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107430359-B Positively-charged single-layer electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2021-08-03 CN disclosed
CN-108139698-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2021-04-27 CN disclosed