Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345845 | 0.84 | GAA (0.40) | HTR2ALMNAHTR2CMAOB | |
| SCHEMBL175131 | 0.79 | HTR2A (0.40) | HTR2ALMNABLMHTR2CDRD2 | |
| SCHEMBL174416 | 0.79 | HTR2A (0.40) | HTR2ALMNABLMHTR2CDRD2 | |
| SCHEMBL10796154 | 0.78 | HTR2A (0.44) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL28329527 | 0.72 | HDAC9 (0.45) | HDAC9KIF11MAOB | |
| SCHEMBL10345420 | 0.70 | HTR2A (0.47) | HTR2AHDAC9HTR2CDRD2SLC6A2 | |
| Phosphoric Acid SCHEMBL10603775 | 0.68 | HTR2A (0.42) | HTR2AHDAC9HTR2CKIF11DRD2 | |
| Fumaric Acid SCHEMBL12504899 | 0.67 | HTR2C (0.64) | HDAC9LMNABLMHTR2CDRD2 | |
| Fumaric Acid SCHEMBL12504903 | 0.67 | HTR2C (0.64) | HDAC9LMNABLMHTR2CDRD2 | |
| Maleic Acid SCHEMBL29496807 | 0.67 | HTR2C (0.64) | HDAC9LMNABLMHTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043980-A2 | METHOD OF REDUCING CRAVING IN MAMMALS | SCHERING CORPORATION (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999021540-A2 | METHOD OF REDUCING CRAVING IN MAMMALS | SCHERING CORPORATION (US) | 1999-05-06 | — | — | WO | disclosed |