Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147695 | 0.78 | HTR2A (0.38) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL18587389 | 0.75 | HTR2A (0.46) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL10345420 | 0.73 | HTR2A (0.47) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL11166802 | 0.73 | HTR2A (0.47) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL9058489 | 0.72 | HTR2A (0.62) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL11503433 | 0.71 | HTR2A (0.42) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL173319 | 0.70 | HTR2A (0.51) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5317898 | 0.69 | HTR2A (0.50) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| Phosphoric Acid SCHEMBL10603775 | 0.68 | HTR2A (0.42) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL829355 | 0.67 | MEN1 (0.42) | HTR2AHTR2CPNMTCD44MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707483-A | 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders | SMITHKLINE BECKMAN CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |