Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | GMNN | O75496 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289397 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2287725 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL11609820 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9210803 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7391537 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9202867 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9214895 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL8714667 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9211158 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2723911 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381769-B2 | Cosmetic compositions using polyether siloxane copolymer network compositions | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-06-03 | — | — | US | claimed |
| US-20050197477-A1 | Cosmetic compositions using polyether siloxane copolymer network compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-09-08 | — | — | US | claimed |
| EP-0786483-B1 | Process for an activated anionic lactam polymerisation | INVENTA AG (CH) | 2000-04-19 | — | — | EP | claimed |
| US-4221879-A | GRAFT POLYMER COMPONENT COMPRISING BUTADIENE MONOMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-09 | — | — | US | claimed |
| CN-116813852-B | Compounds, polymers and lithographic medium compositions for use in lithographic medium compositions | 嘉庚创新实验室 | 2024-04-19 | — | — | CN | disclosed |
| CN-116554444-B | Polymer for lithographic medium composition and lithographic medium composition | 嘉庚创新实验室 | 2024-03-29 | — | — | CN | disclosed |
| CN-116813852-A | Compounds, polymers and lithographic medium compositions for use in lithographic medium compositions | 嘉庚创新实验室 | 2023-09-29 | — | — | CN | disclosed |
| CN-116829562-A | Macrocyclic compound, pharmaceutical composition and application thereof | 深圳国顺康医药科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116554444-A | Polymer for lithographic medium composition and lithographic medium composition | 嘉庚创新实验室 | 2023-08-08 | — | — | CN | disclosed |
| CN-111902417-B | Diaryl macrocyclic compound, pharmaceutical composition and application thereof | 北京普祺医药科技股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-113149993-A | Pyrrolopyrimidine derivative compound, pharmaceutical composition and application thereof | 北京普祺医药科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-109867675-B | Pyrrolopyrimidine derivative compound, pharmaceutical composition and application thereof | 北京普祺医药科技有限公司 | 2021-01-19 | — | — | CN | disclosed |
| US-5019286-A | Oil additives | EXXON CHEMICAL PATENTS, INC. (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0014515-B2 | HARDENABLE COMPOSITIONS, PROCESS TO MAKE A SHAPED ARTICLE THEREFROM AND DENTAL APPLIANCE COMPRISING IT | DENTSPLY INTERNATIONAL, INC. (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4935442-A | Tetrahydrofuran-containing macrocyclic polyether carboxylic acids | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4698373-A | HARDENABLE ACRYLIC BLENDS CONTAINING SWELLABLE POLYMER PARTICLES; INTERPENETRATING POLYMER NETWORKS; WEAR RESISTANCE | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0014515-B1 | HARDENABLE COMPOSITIONS, PROCESS TO MAKE A SHAPED ARTICLE THEREFROM AND DENTAL APPLIANCE COMPRISING IT | DENTSPLY INTERNATIONAL, INC. (US) | 1984-03-14 | — | — | EP | disclosed |
| US-4396377-A | BLEND OF CROSSLINKED POLYMER, POLYMERIZABLE MONOMER AND CROSSLINKING AGENT HARDENED INTO SHAPED BODY | DENTSPLY RESEARCH & DEVELOPMENT CORPORATION (US) | 1983-08-02 | — | — | US | disclosed |
| US-4396476-A | ACRYLIC ESTER HOMO- AND COPOLYMERS; PROSTHETICS; DENISTRY; MOLDING MATERIALS | DENTSPLY RESEARCH & DEVELOPMENT CORPORATION (US) | 1983-08-02 | — | — | US | disclosed |