Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202291 | 1.00 | CHRNB2 (0.52) | CHRNB2CHRNA4KDM4ECYP1A2CYP2D6 | |
| SCHEMBL6583353 | 0.85 | CHRNB2 (0.55) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6587677 | 0.84 | CHRNB2 (0.53) | CHRNB2CHRNA4 | |
| SCHEMBL6582481 | 0.83 | CHRNB2 (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL7671098 | 0.83 | CHRNB2 (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL7825469 | 0.80 | KDM4E (0.54) | CHRNB2CHRNA4KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7816677 | 0.80 | KDM4E (0.54) | CHRNB2CHRNA4KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7824395 | 0.80 | KDM4E (0.54) | CHRNB2CHRNA4KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7817303 | 0.80 | KDM4E (0.54) | CHRNB2CHRNA4KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7477214 | 0.80 | KDM4E (0.54) | CHRNB2CHRNA4KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127386-A | STIMULANTS, NEUROTRANSMITTERS, CHOLINERGIC AGENTS | ABBOTT LABORATORIES (US) | 2000-10-03 | — | — | US | claimed |