Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146916 | 0.90 | GRM2 (0.43) | GRM2F10 | |
| SCHEMBL8153281 | 0.87 | ITGB3 (0.47) | GRM2F10 | |
| SCHEMBL8151634 | 0.87 | F10 (0.48) | GRM2F10 | |
| SCHEMBL8146751 | 0.86 | GRM2 (0.48) | GRM2 | |
| SCHEMBL8146882 | 0.86 | GRM2 (0.56) | GRM2 | |
| SCHEMBL8151961 | 0.85 | GRM2 (0.47) | GRM2 | |
| SCHEMBL8147704 | 0.85 | GRM2 (0.47) | GRM2 | |
| SCHEMBL8146486 | 0.85 | GRM2 (0.47) | GRM2 | |
| SCHEMBL8147894 | 0.84 | GRM2 (0.52) | GRM2 | |
| SCHEMBL8151676 | 0.83 | GRM2 (0.47) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028090-A | Adhesion receptor antagonists III | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |
| US-5723480-A | Adhesion receptor antagonists III | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-03 | — | — | US | disclosed |
| US-5561148-A | Adhesion receptor antagonists III | MERCK PATENT GESELLSCHAFT MIT BESHRANKTER HAFTUNG (DE) | 1996-10-01 | — | — | US | disclosed |