Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 13/20 | 0.80 |
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164500 | 1.00 | NAAA (0.80) | NAAAFAAHL3MBTL1MEN1KMT2A | |
| SCHEMBL8163713 | 1.00 | NAAA (0.80) | NAAAFAAHL3MBTL1MEN1KMT2A | |
| SCHEMBL8157548 | 0.95 | NAAA (0.82) | NAAAFAAHL3MBTL1MEN1KMT2A | |
| SCHEMBL8149080 | 0.95 | NAAA (0.82) | NAAAFAAHL3MBTL1MEN1KMT2A | |
| SCHEMBL8158609 | 0.89 | NAAA (0.64) | NAAAFAAH | |
| SCHEMBL7698014 | 0.89 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL8156788 | 0.89 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL8157214 | 0.89 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19612753 | 0.89 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL8149956 | 0.89 | NAAA (1.00) | NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6086905-A | Topical compositions useful as skin penetration barriers | DISCOVERY THERAPEUTICS, INC. | 2000-07-11 | — | — | US | disclosed |