Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494650 | 0.86 | SMN1; SMN2 (0.47) | ALDH1A1LMNATYRESRRGMEN1 | |
| SCHEMBL20138639 | 0.85 | ESR1 (0.55) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL29074082 | 0.84 | ESR1 (0.50) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL28915433 | 0.84 | NPC1 (0.46) | ALDH1A1LMNAHPGDTSHRMEN1 | |
| SCHEMBL1492728 | 0.83 | CYP2C19 (0.50) | ALDH1A1TSHRCYP1A2KMT2ACHRM2 | |
| SCHEMBL15827159 | 0.82 | CYP26B1 (0.40) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL5794046 | 0.82 | KDM4E (0.44) | ALDH1A1HPGDMEN1CYP1A2KMT2A | |
| SCHEMBL30954170 | 0.82 | ESR1 (0.50) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL20556837 | 0.82 | MIF (0.48) | CYP3A4TSHRMEN1CYP1A2KMT2A | |
| SCHEMBL4514966 | 0.82 | MEN1 (0.40) | ESR1ESR2CYP3A4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159674-A | 2-benzene alkyl amid compound and preparation method, medical composition and use thereof | SUZHOU ANNUO BIOLOG MEDICAL TECHNOLOGY CO LTD | 2013-06-19 | — | — | CN | disclosed |
| US-6043284-A | ACYL COENZYME A: CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS | GLAXO WELLCOME INC. (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0806417-B1 | Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements | SUMITOMO CHEMICAL CO (JP) | 2000-03-08 | — | — | EP | disclosed |
| US-5693251-A | LIQUID CRYSTAL DISPLAYS; HIGH SPEED RESPONSE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0806417-A1 | Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |
| US-5389293-A | Light switches | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0360622-A2 | Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-28 | — | — | EP | disclosed |