SCHEMBL1492728

SCHEMBL1492728

CCC(C)(C(=O)O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.50
HIF1A Q16665 1/20 0.50
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 2/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
CYP2D6 P10635 1/20 0.42
RIPK1 Q13546 3/20 0.42
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28727593 0.98 CYP2C19 (0.48) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL28938744 0.98 CYP2C19 (0.48) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL28729111 0.96 CYP2C19 (0.47) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL21359975 0.89 SMN1; SMN2 (0.44) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL27934590 0.85 ALDH1A1 (0.49) KMT2ACYP1A2ALDH1A1
SCHEMBL6722251 0.85 CYP2C19 (0.48) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL8494650 0.85 SMN1; SMN2 (0.47) MAPTKMT2ACYP1A2HDAC3HDAC1
SCHEMBL28682985 0.85 CYP2C19 (0.48) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL9424924 0.84 MAPT (0.51) CYP2C19MAPTKMT2ACYP1A2HDAC3
SCHEMBL2030597 0.83 MAPT (0.59) CYP2C19HIF1AMAPTKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115290793-B Method for judging storage time of semi-fermented type fermented bean curd 上海应用技术大学 2025-03-21 CN claimed
CN-115290793-A Method for judging storage time of semi-fermented strong-smelling preserved bean curd 上海应用技术大学 2022-11-04 CN claimed
EP-3884018-A1 JASMOL Symrise AG (DE) 2021-09-29 EP claimed
CN-109809962-A A kind of new synthetic method of 2- (4- bromomethyl) phenylpropionic acid 盘锦格林凯默科技有限公司 2019-05-28 CN claimed
CN-108290871-A Isoindolinone inhibitors of MDM2-P53 interaction with anti-cancer activity 阿斯泰克斯治疗有限公司 2018-07-17 CN claimed
EP-2600736-B1 FOOD PRODUCT COMPRISING A BASE INGREDIENT COMPRISING CEREAL SEEDS MISTER BIO FOOD S R L (IT) 2018-07-04 EP claimed
EP-2033635-A1 Short-chain fatty acid derivatives for treating pruritus Asan Laboratories Company (Cayman) Limited (CN) 2009-03-11 EP claimed
CN-101380317-A Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV (CN) 2009-03-11 CN claimed
US-20080107646-A1 Administering phenylbutyric acid derivative and pharmaceutically acceptable carrier Sunny Pharmtech Inc. (TW) 2008-05-08 US claimed
CN-101166730-A Cinnoline compounds and their use as liver X receptor modilators WYETH CORP (US) 2008-04-23 CN claimed
CN-1914173-A Quinolines useful in treating cardiovascular disease WYETH CORP (US) 2007-02-14 CN claimed
US-6403646-B1 ADMINISTERING PHENYLBUTYRIC ACID OR DERIVATIVES TO TREAT LIVER DISEASE AND EMPHYSEMA CAUSED BY PROTEASE INHIBITOR TYPE Z MUTATION; STIMULATES SECRETION WITHOUT INCREASING SYNTHESIS OF PROTEIN PERLMUTTER DAVID H (US) 2002-06-11 US claimed
JP-60081108-A None JP disclosed
CN-119923418-A Methacrylic acid-containing composition, method for producing methacrylic acid ester, polymerizable composition, and method for producing methacrylic acid polymer 三菱化学株式会社 2025-05-02 CN disclosed
US-20220411410-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS VERTEX PHARMACEUTICALS INCORPORATED 2022-12-29 US disclosed
CN-115290793-A Method for judging storage time of semi-fermented strong-smelling preserved bean curd 上海应用技术大学 2022-11-04 CN disclosed
US-3933898-A ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
JP-S0681105-A 0001-01-01 JP disclosed
JP-S0681108-A 0001-01-01 JP disclosed
JP-S0681103-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411410-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS CFTR, ABCB1, ABCC2 CYP2C19 1915/4885HIF1A 1715/4885MAPT 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.