Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8448006 | 0.78 | — | — | |
| SCHEMBL8152932 | 0.76 | TAAR1 (0.34) | TAAR1HRH3 | |
| Hydrochloric Acid SCHEMBL3644219 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL6332598 | 0.73 | — | — | |
| SCHEMBL7977764 | 0.73 | TAAR1 (0.32) | TAAR1HRH3CHRNA7 | |
| Hydrochloric Acid SCHEMBL4633244 | 0.73 | TAAR1 (0.32) | TAAR1HRH3 | |
| Hydrochloric Acid SCHEMBL8148699 | 0.73 | TAAR1 (0.32) | TAAR1HRH3 | |
| Hydrochloric Acid SCHEMBL6340287 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL8453417 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6332811 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117811-A | CATALYSTS FOR POLYMERIZATION OF OLEFINS | DSM N.V. (NL) | 2000-09-12 | — | — | US | disclosed |