Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cetalkonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetalkonium SCHEMBL8149290 | 1.00 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Cetalkonium SCHEMBL6380754 | 1.00 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Benzododecinium SCHEMBL8150784 | 1.00 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Benzododecinium SCHEMBL6379291 | 1.00 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Cetalkonium SCHEMBL8148836 | 1.00 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Benzododecinium SCHEMBL8150421 | 1.00 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Benzododecinium SCHEMBL8161443 | 1.00 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Miristalkonium Ion SCHEMBL17435024 | 1.00 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Benzododecinium SCHEMBL17435033 | 0.96 | DNM1 (0.74) | DNM1MEN1KMT2ATP53MAPK1 | |
| Miristalkonium Ion SCHEMBL23754683 | 0.95 | DNM1 (0.65) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087303-A | METAL-FREE WOOD PRESERVATIVE CONSISTS OF A BIOCIDE CONTAINING DIMETHYL-DI-C8-C12 ALKYLAMMONIUM CARBOXYLATE OR BORATE AND AN AQUEOUS SOLVENT | LONZA, INC. (US) | 2000-07-11 | — | — | US | disclosed |
| US-5891921-A | WOOD PRESERVATIVE SYSTEMS COMPRISING BIOCIDAL EFFECTIVE AMOUNT OF QUATERNARY AMMONIUM CARBOXYLATE, ALKYL QUATERNARY AMMONIUM BORATE, AND SOLVENT | LONZA INC. (US) | 1999-04-06 | — | — | US | disclosed |
| US-5700841-A | WOOD PRESERVATIVES | LONZA INC. (US) | 1997-12-23 | — | — | US | disclosed |
| US-5641726-A | WOOD PRESERVATIVES | LONZA, INC. (US) | 1997-06-24 | — | — | US | disclosed |